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乳糜泻。临床诊断的重新评估。

Coeliac disease. Reappraisal of clinical diagnosis.

作者信息

Cook D M, Evans N, Lloyd A, Stewart J S

出版信息

Arch Dis Child. 1971 Oct;46(249):705-8. doi: 10.1136/adc.46.249.705.

Abstract

Twelve children previously diagnosed as having coeliac disease on criteria now regarded as incomplete have been reinvestigated. Six were found to have an intestinal mucosal lesion characteristic of coeliac disease. All but one had been asymptomatic on a normal diet for more than 18 months. Response to diet fails to distinguish between coeliacs and non-coeliacs. Establishing the diagnosis of coeliac disease by intestinal biopsy is essential, since even apparently symptomless individuals are at considerable risk.

摘要

对12名先前根据目前认为不完整的标准被诊断为患有乳糜泻的儿童进行了重新检查。发现其中6名儿童有乳糜泻特有的肠道黏膜病变。除一人外,其他人在正常饮食情况下超过18个月都没有症状。饮食反应无法区分乳糜泻患者和非乳糜泻患者。通过肠道活检来确诊乳糜泻至关重要,因为即使是明显无症状的个体也面临相当大的风险。

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本文引用的文献

1
SERUM-FOLIC-ACID IN RECURRENT ABORTIONS.复发性流产中的血清叶酸
Lancet. 1965 Mar 27;1(7387):670-2. doi: 10.1016/s0140-6736(65)91826-x.
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AETIOLOGICAL FACTORS IN ABRUPTIO PLACENTAE.胎盘早剥的病因
Br Med J. 1963 Dec 7;2(5370):1430-6. doi: 10.1136/bmj.2.5370.1430.
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Studies on the folic acid activity of human serum.人体血清叶酸活性的研究。
J Clin Pathol. 1961 Jul;14(4):335-44. doi: 10.1136/jcp.14.4.335.

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