Cook D M, Evans N, Lloyd A, Stewart J S
Arch Dis Child. 1971 Oct;46(249):705-8. doi: 10.1136/adc.46.249.705.
Twelve children previously diagnosed as having coeliac disease on criteria now regarded as incomplete have been reinvestigated. Six were found to have an intestinal mucosal lesion characteristic of coeliac disease. All but one had been asymptomatic on a normal diet for more than 18 months. Response to diet fails to distinguish between coeliacs and non-coeliacs. Establishing the diagnosis of coeliac disease by intestinal biopsy is essential, since even apparently symptomless individuals are at considerable risk.
对12名先前根据目前认为不完整的标准被诊断为患有乳糜泻的儿童进行了重新检查。发现其中6名儿童有乳糜泻特有的肠道黏膜病变。除一人外，其他人在正常饮食情况下超过18个月都没有症状。饮食反应无法区分乳糜泻患者和非乳糜泻患者。通过肠道活检来确诊乳糜泻至关重要，因为即使是明显无症状的个体也面临相当大的风险。
