Smith S E, Littlewood J M
Clin Radiol. 1977 Nov;28(6):629-34. doi: 10.1016/s0009-9260(77)80043-3.
Prospective experience over five years is described in assessing the two-film barium meal as a test for the exclusion of untreated celiac disease in children in order to try to make jejunal biopsy unnecessary. 287 meals were examined in children between 3 months and 10 years of age with a variety of gastro-intestinal symptoms and signs that might be attributed to celiac disease. From the two-film barium meal the calibre and transverse mucosal folds of the upper small bowel were measured. In 48 children with untreated coeliace disease there were only three (6%) with negative two-film barium meals. In 45 children with malabsorption from causes other than coeliac disease, there were four (9%) with negative two-film barium meals. It is concluded that the two-film barium meal is a reasonably reliable test for the exclusion of untreated coeliac disease in children. It is simple, cheap, safe and economical of radiological time, and it compares favourably in accuracy with other screening tests, other than jejunal biopsy.
本文描述了一项为期五年的前瞻性研究，旨在评估双对比钡餐检查作为排除儿童未经治疗的乳糜泻的一项检测方法，以避免空肠活检的必要性。对年龄在3个月至10岁之间、有各种可能归因于乳糜泻的胃肠道症状和体征的儿童进行了287次钡餐检查。通过双对比钡餐测量了上消化道小肠的管径和横向黏膜皱襞。在48例未经治疗的乳糜泻患儿中，只有3例（6%）双对比钡餐检查结果为阴性。在45例由非乳糜泻原因引起吸收不良的儿童中，有4例（9%）双对比钡餐检查结果为阴性。研究得出结论，双对比钡餐检查是排除儿童未经治疗的乳糜泻的一种相当可靠的检测方法。它简单、便宜、安全，且节省放射检查时间，在准确性方面与除空肠活检之外的其他筛查试验相比具有优势。
