Altschuler R A
J Histochem Cytochem. 1979 Nov;27(11):1548-50. doi: 10.1177/27.11.512348.
A morphometric analysis of the effect of differential experiences on synapses was performed in area CA3 of the rat hippocampus. Two methods of quantitation that used a superimposed lattice grid were employed. In the first method squares overlying synapses were measured as a proportion of the total number of squares scanned; in the second method intersections of lattice lines with synapses were counted as a proportion of the total length of lines. Both measures showed that rats which were housed in an enriched environment and received 10 weeks of training had a significant increase in total area of synaptic contacts compared to both nonenriched controls and a croup with increased motor activity.
在大鼠海马体的CA3区对不同经历对突触的影响进行了形态计量分析。采用了两种使用叠加格子网格的定量方法。在第一种方法中，覆盖突触的方格被测量为扫描的方格总数的比例；在第二种方法中，格线与突触的交点被计数为线总长度的比例。两种测量方法均显示，与未丰富环境的对照组和运动活动增加的一组相比，饲养在丰富环境中并接受10周训练的大鼠突触接触总面积显著增加。
