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使用锝-99m进行甲状腺功能的常规评估。

Use of 99 Tc m for the routine assessment of thyroid function.

作者信息

Goolden A W, Glass H I, Williams E D

出版信息

Br Med J. 1971 Nov 13;4(5784):396-9. doi: 10.1136/bmj.4.5784.396.

Abstract

(99)Tc(m)-pertechnetate is concentrated in the thyroid in the same way as iodide but it does not become organically bound. The uptake of (99)Tc(m) is a measure of the thyroid trap, and this measurement is satisfactory as a routine test in the diagnosis of thyrotoxicosis. The reproducibility of the method is such that suppression tests can be carried out when necessary even when uptake is within the normal range of 0.4-3%. (99)Tc(m) gives a low radiation dose to the thyroid and has certain other advantages over radioactive isotopes of iodine for early thyroid uptake measurements. It is particularly suitable when serial tests of thyroid function are required during treatment with an antithyroid drug.

摘要

(99)锝-高锝酸盐与碘化物一样在甲状腺中浓聚,但它不会与甲状腺组织有机结合。(99)锝的摄取是甲状腺摄取功能的一种衡量指标,作为甲状腺毒症诊断的常规检查,这种测量结果令人满意。该方法的可重复性使得即使摄取率在正常范围0.4%-3%之内,必要时也可进行抑制试验。(99)锝对甲状腺的辐射剂量较低,与碘的放射性同位素相比,在早期甲状腺摄取测量方面还有其他一些优势。在使用抗甲状腺药物治疗期间需要对甲状腺功能进行系列检查时,它特别适用。

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Technetium uptake in the management of thyrotoxicosis.锝摄取在甲状腺毒症治疗中的应用。
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Technetium-99 m in the diagnosis of thyrotoxicosis.锝-99m在甲状腺毒症诊断中的应用
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本文引用的文献

2
A diagnostic radioiodine uptake test in patients receiving antithyroid drug.
J Clin Endocrinol Metab. 1960 Dec;20:1601-7. doi: 10.1210/jcem-20-12-1601.
4
Measurement of the uptake of 99mTc by the thyroid.
Br J Radiol. 1968 Dec;41(492):896-8. doi: 10.1259/0007-1285-41-492-896.
5
Thyroidal uptake and turnover of the pertechnetate ion in normal and hyperthyroid subjects.
J Clin Endocrinol Metab. 1968 Apr;28(4):575-81. doi: 10.1210/jcem-28-4-575.

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