Silverberg R, Naparstek Y, Lewis B S, Levy M
J Neurol Neurosurg Psychiatry. 1979 Oct;42(10):910-3. doi: 10.1136/jnnp.42.10.910.
A patient with Shy-Drager syndrome who presented with severe angina pectoris is described. Special investigations of his autonomic nervous system showed sympathetic and parasympathetic dysfunction with supersensitive end-organ response. Sympathetic dysfunction manifested as labile hypertension, severe postural hypotension, and inadequate heart rate response to atropine and the Valsalva manoeuvre. These changes in blood pressure were accompanied by severe disabling angina pectoris. Selective coronary angiography showed normal coronary arteries. It is suggested that angina pectoris resulted from the inadequate circulatory response and is another clinical manifestation of the Shy-Drager syndrome.
本文描述了一名患有Shy-Drager综合征且伴有严重心绞痛的患者。对其自主神经系统进行的特殊检查显示，交感神经和副交感神经功能障碍，且终末器官反应超敏。交感神经功能障碍表现为血压波动、严重体位性低血压，以及对阿托品和瓦尔萨尔瓦动作的心率反应不足。这些血压变化伴有严重的致残性心绞痛。选择性冠状动脉造影显示冠状动脉正常。提示心绞痛是由于循环反应不足所致，是Shy-Drager综合征的另一种临床表现。
