新生兔棕色脂肪中存在周转率快的甘油酯池的证据。
Evidence for the presence of a pool of glycerides with a rapid rate of turnover in brown fat from newborn rabbits.
作者信息
Knight B L
出版信息
Biochem J. 1971 Jul;123(4):485-91. doi: 10.1042/bj1230485.
Abstract
- The specific radioactivity of [(14)C]glycerol released during the incubation of brown fat with [(14)C]glucose is much greater than that of the tissue lipid glycerol. 2. From a study of the release of [(14)C]glycerol from pre-labelled brown fat, it is concluded that the tissue contains a pool of glycerides with a higher rate of turnover than those in the main lipid store. 3. This pool contains newly synthesized glycerides, has a half-life of 25-30min and supplies about 25% of the glycerol liberated by brown fat. 4. Thus, a significant fraction of the total (14)C incorporated from glucose into brown-fat lipids is released as [(14)C]glycerol during an incubation.
摘要
- 棕色脂肪与[¹⁴C]葡萄糖一起孵育期间释放的[¹⁴C]甘油的比放射性远高于组织脂质甘油的比放射性。2. 通过对预先标记的棕色脂肪释放[¹⁴C]甘油的研究得出结论，该组织中存在一组甘油酯，其周转速率高于主要脂质储存中的甘油酯。3. 这一组包含新合成的甘油酯，半衰期为25 - 30分钟，并提供棕色脂肪释放的甘油的约25%。4. 因此，在孵育期间，从葡萄糖掺入棕色脂肪脂质中的总¹⁴C的很大一部分以[¹⁴C]甘油的形式释放出来。
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引用本文的文献
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The effect of noradrenaline on glyceride synthesis and oxidative metabolism in vitro in the brown fat of newborn rabbits.去甲肾上腺素对新生兔棕色脂肪体外甘油酯合成及氧化代谢的影响。
Biochem J. 1971 Nov;125(1):1-8. doi: 10.1042/bj1250001.
本文引用的文献
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