Enzyme inhibitors. 23. Syntheses of 9-(substituted aralkyl)-6-substituted purines as inhibitors of adenosine deaminase.
作者信息
Schaeffer H J, Odin E, Bittner S
出版信息
J Pharm Sci. 1971 Aug;60(8):1184-8. doi: 10.1002/jps.2600600814.
PMID:5127092
Abstract
摘要
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1
Enzyme inhibitors. 23. Syntheses of 9-(substituted aralkyl)-6-substituted purines as inhibitors of adenosine deaminase.
J Pharm Sci. 1971 Aug;60(8):1184-8. doi: 10.1002/jps.2600600814.
2
ENZYME INHIBITORS. V. THE SYNTHESES OF 6-SUBSTITUTED-(9-HYDROXYALKYL)PURINES AND THEIR EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.
Biochemistry. 1965 Jan;4:71-6. doi: 10.1021/bi00877a013.
3
Enzyme inhibitors. XX. Studies on the hydrophobic and hydroxyl binding regions of adenosine deaminase. 9-(2-m-Bromoacetamidophenethyl)adenine, a new irreversible inhibitor of adenosine deaminase.酶抑制剂。XX。腺苷脱氨酶疏水及羟基结合区域的研究。9-(2-间溴乙酰氨基苯乙基)腺嘌呤，一种新型不可逆腺苷脱氨酶抑制剂。
J Med Chem. 1968 Jan;11(1):21-6. doi: 10.1021/jm00307a004.
4
Enzyme inhibitors. XXI. Hydrophobic and hydroxylic binding sites of adenosine deaminase.
J Pharm Sci. 1967 Dec;56(12):1586-90. doi: 10.1002/jps.2600561210.
5
ENZYME INHIBITORS. VI. STUDIES ON THE BULK TOLERANCE OF ADENOSINE DEAMINASE FOR 6-SUBSTITUTED AMINO-9-(3-HYDROXYPROPYL)PURINES.酶抑制剂。VI。腺苷脱氨酶对6-取代氨基-9-(3-羟丙基)嘌呤的大量耐受性研究。
J Med Chem. 1965 Jan;8:33-5. doi: 10.1021/jm00325a008.
6
Enzyme inhibitors. XIV. Syntheses of some 9-(m-substituted benzyl)-6-substituted purines and their evaluation as inhibitors of adenosine deaminase.酶抑制剂。十四。某些9-（间位取代苄基）-6-取代嘌呤的合成及其作为腺苷脱氨酶抑制剂的评价。
J Pharm Sci. 1966 Sep;55(9):929-35. doi: 10.1002/jps.2600550912.
7
Enzyme inhibitors. XIX. The synthesis of some 1-hydroxy-2-hydroxymethyl-4-(6-substituted-9-purinyl)cyclohexanes as nucleoside analogs.酶抑制剂。十九。一些1-羟基-2-羟甲基-4-（6-取代-9-嘌呤基）环己烷作为核苷类似物的合成。
J Med Chem. 1968 Jan;11(1):15-20. doi: 10.1021/jm00307a003.
8
ENZYME INHIBITORS. 3. SYNTHESES OF CIS-(6-SUBSTITUTED-9-PURINYL)CYCLOALKYLCARBINOLS AS ADENOSINE DEAMINASE INHIBITORS.酶抑制剂。3. 作为腺苷脱氨酶抑制剂的顺式-（6-取代-9-嘌呤基）环烷基甲醇的合成。
J Pharm Sci. 1964 Dec;53:1510-5. doi: 10.1002/jps.2600531217.
9
ENZYME INHIBITORS. IV. SYNTHESES OF 6-SUBSTITUTED-9-(-5-DEOXY-BETA-D-XYLOFURANOSYL) PURINES AND THEIR EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.酶抑制剂。IV. 6-取代-9-(-5-脱氧-β-D-呋喃木糖基)嘌呤的合成及其作为腺苷脱氨酶抑制剂的评价。
J Pharm Sci. 1965 Jan;54:15-20. doi: 10.1002/jps.2600540105.
10
ENZYME INHIBITORS . VII. SYNTHESES OF TRANS-4-(6-SUBSTITUTED-9-PURINYL)CYCLOHEXYLCARBINOLS AND EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.酶抑制剂。VII。反式-4-(6-取代-9-嘌呤基)环己基甲醇的合成及其作为腺苷脱氨酶抑制剂的评价。
J Pharm Sci. 1965 Mar;54:421-4. doi: 10.1002/jps.2600540316.
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