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ENZYME INHIBITORS. V. THE SYNTHESES OF 6-SUBSTITUTED-(9-HYDROXYALKYL)PURINES AND THEIR EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.

作者信息

SCHAEFFER H J, BHARGAVA P S

出版信息

Biochemistry. 1965 Jan;4:71-6. doi: 10.1021/bi00877a013.

DOI:10.1021/bi00877a013
PMID:14285247
Abstract
摘要

相似文献

1
ENZYME INHIBITORS. V. THE SYNTHESES OF 6-SUBSTITUTED-(9-HYDROXYALKYL)PURINES AND THEIR EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.
Biochemistry. 1965 Jan;4:71-6. doi: 10.1021/bi00877a013.
2
ENZYME INHIBITORS. VI. STUDIES ON THE BULK TOLERANCE OF ADENOSINE DEAMINASE FOR 6-SUBSTITUTED AMINO-9-(3-HYDROXYPROPYL)PURINES.酶抑制剂。VI。腺苷脱氨酶对6-取代氨基-9-(3-羟丙基)嘌呤的大量耐受性研究。
J Med Chem. 1965 Jan;8:33-5. doi: 10.1021/jm00325a008.
3
ENZYME INHIBITORS. IV. SYNTHESES OF 6-SUBSTITUTED-9-(-5-DEOXY-BETA-D-XYLOFURANOSYL) PURINES AND THEIR EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.酶抑制剂。IV. 6-取代-9-(-5-脱氧-β-D-呋喃木糖基)嘌呤的合成及其作为腺苷脱氨酶抑制剂的评价。
J Pharm Sci. 1965 Jan;54:15-20. doi: 10.1002/jps.2600540105.
4
ENZYME INHIBITORS . VII. SYNTHESES OF TRANS-4-(6-SUBSTITUTED-9-PURINYL)CYCLOHEXYLCARBINOLS AND EVALUATION AS INHIBITORS OF ADENOSINE DEAMINASE.酶抑制剂。VII。反式-4-(6-取代-9-嘌呤基)环己基甲醇的合成及其作为腺苷脱氨酶抑制剂的评价。
J Pharm Sci. 1965 Mar;54:421-4. doi: 10.1002/jps.2600540316.
5
ENZYME INHIBITORS. 3. SYNTHESES OF CIS-(6-SUBSTITUTED-9-PURINYL)CYCLOALKYLCARBINOLS AS ADENOSINE DEAMINASE INHIBITORS.酶抑制剂。3. 作为腺苷脱氨酶抑制剂的顺式-（6-取代-9-嘌呤基）环烷基甲醇的合成。
J Pharm Sci. 1964 Dec;53:1510-5. doi: 10.1002/jps.2600531217.
6
Enzyme inhibitors. 8. Studies on the mode of binding of some 6-substituted 9-(hydroxyalkyl)purines to adenosine deaminase.酶抑制剂。8. 某些6-取代9-（羟烷基）嘌呤与腺苷脱氨酶结合模式的研究。
J Med Chem. 1965 Jul;8(4):502-6. doi: 10.1021/jm00328a020.
7
Enzyme inhibitors. 23. Syntheses of 9-(substituted aralkyl)-6-substituted purines as inhibitors of adenosine deaminase.
J Pharm Sci. 1971 Aug;60(8):1184-8. doi: 10.1002/jps.2600600814.
8
ENZYME INHIBITORS. II. SYNTHESIS OF TRANS-3-(6-SUBSTITUTED-9-PURINYL)CYCLOHEXANOLS AS ADENOSINE DEAMINASE INHIBITORS.酶抑制剂。II. 作为腺苷脱氨酶抑制剂的反式-3-(6-取代-9-嘌呤基)环己醇的合成
J Pharm Sci. 1964 Nov;53:1371-4. doi: 10.1002/jps.2600531120.
9
ENZYME INHIBITORS. I. INHIBITION OF ADENOSINE DEAMINASE BY ISOSTERIC NUCLEOSIDES.
J Pharm Sci. 1964 Nov;53:1368-70. doi: 10.1002/jps.2600531119.
10
Enzyme inhibitors. XI. Mode of binding of the hydroxyl group of some 9-(hydroxyalkyl)-adenines to adenosine deaminase.酶抑制剂。XI. 某些9-（羟烷基）腺嘌呤的羟基与腺苷脱氨酶的结合方式。
J Pharm Sci. 1965 Jul;54(7):978-82. doi: 10.1002/jps.2600540706.

引用本文的文献

1
New trends in nucleoside biotechnology.核苷生物技术的新趋势。
Acta Naturae. 2010 Jul;2(2):36-59.
2
Structural assignment of 6-oxy purine derivatives through computational modeling, synthesis, X-ray diffraction, and spectroscopic analysis.通过计算建模、合成、X 射线衍射和光谱分析对 6-氧嘌呤衍生物进行结构分配。
J Phys Chem B. 2010 May 27;114(20):6968-72. doi: 10.1021/jp100039p.
3
Adenosine deaminase inhibitors: their role in chemotherapy and immunosuppression.腺苷脱氨酶抑制剂：它们在化疗和免疫抑制中的作用。
Cancer Chemother Pharmacol. 1980;4(4):227-35. doi: 10.1007/BF00255266.
4
Effect of 9-beta-D-arabinofuranosyladenine on polymer synthesis in a polyauxotrophic strain of Escherichia coli.9-β-D-阿拉伯呋喃糖基腺嘌呤对大肠杆菌多营养缺陷型菌株中聚合物合成的影响。
J Bacteriol. 1966 Sep;92(3):558-64. doi: 10.1128/jb.92.3.558-564.1966.
5
[Competitive inhibition of adenosine aminase as a possible cause of the coronary dilating effects of a pyrimidopyrimidine combination].[嘧啶并嘧啶组合产生冠状动脉扩张作用的可能原因：腺苷氨酶的竞争性抑制]
Naunyn Schmiedebergs Arch Pharmakol Exp Pathol. 1966;255(1):107-19.