McRae D, Shaw A
J Pediatr Surg. 1979 Oct;14(5):612-4. doi: 10.1016/s0022-3468(79)80152-9.
A child with mediastinal and supraclavicular ganglioneuroma, heterochromia iridis, and Horner's syndrome is described. The authors postulate that the thoracic neoplasm originated as a congenital neuroblastoma with metastasis to the supraclavicular lymph nodes and subsequent benign transformation, and that the ocular abnormalities resulted from sympathetic ganglion injury by the tumor in infancy. This seems to be the first published report of such ocular abnormalities associated with mediastinal ganglioneuroma.
本文描述了一名患有纵隔和锁骨上神经节神经瘤、虹膜异色症和霍纳综合征的儿童。作者推测,胸内肿瘤起源于先天性神经母细胞瘤,已转移至锁骨上淋巴结,随后发生良性转化,眼部异常是由于婴儿期肿瘤对交感神经节的损伤所致。这似乎是首例关于纵隔神经节神经瘤相关眼部异常的报道。