Efremushkin G G, Goriacheva A V, Kolomenskaia T I, Solomatina L G, Ovcharenko R P
Kardiologiia. 1979 Nov;19(11):46-51.
The lipoprotein spectrum was studied in polyacrylamide gel and by thin-layer chromatography on silica gel in 236 patients with myocardial infarction in different periods of the disease, in 45 patients with unstable angina pectoris, in 75 healthy persons and in 8 dogs with experimental myocardial infarction. Besides an increase in the concentration of cholesterol and triglycerides and a decrease in the level of diglycerides in blood serum, there is a disturbance in the ratio of phospholipid fractions, mainly in myocardial infarction. The level of pre-beta-lipoproteins was increased in the acute period of myocardial infarction, the level of beta-lipoproteins in the subacute period. Complications and concomitant inflammatory diseases were attended by a higher level of beta-lipoproteins. A connection was noted between the lipoprotein spectrum, predominantly of the pre-beta-fraction, and the ABO phenotype and the season.
在236例处于疾病不同阶段的心肌梗死患者、45例不稳定型心绞痛患者、75名健康人和8只实验性心肌梗死犬中，采用聚丙烯酰胺凝胶法和硅胶薄层层析法研究了脂蛋白谱。除血清中胆固醇和甘油三酯浓度升高以及甘油二酯水平降低外，主要在心肌梗死患者中还存在磷脂组分比例紊乱的情况。前β-脂蛋白水平在心肌梗死急性期升高，β-脂蛋白水平在亚急性期升高。并发症和伴随的炎症性疾病患者的β-脂蛋白水平更高。研究发现脂蛋白谱（主要是前β组分）与ABO血型表型及季节之间存在联系。
