Anand L C, Rathore B S
Lepr India. 1979 Jul;51(3):358-62.
35 cases of lepromatous leprosy were studied to evaluate the effective blood level and long depot action of acedapsone (DADDS). It was revealed that serum level of this drug is maintained well above the minimum inhibitory concentration upto 60 days following single intramuscular injection. No significant untoward effects of the drug were encountered except one case of Erythema Nodosum Leprosum and six patients with mild reactional symptoms in the form of fever and arthralgia.
对35例瘤型麻风患者进行了研究，以评估醋氨苯砜（二乙酰氨苯砜，DADDS）的有效血药浓度及长效作用。结果显示，单次肌内注射后，该药物的血清浓度在60天内均维持在最低抑菌浓度之上。除1例结节性红斑麻风患者及6例出现发热和关节痛等轻度反应症状的患者外，未发现该药物有明显的不良反应。
