Bassett D C
J Clin Pathol. 1971 Dec;24(9):798-800. doi: 10.1136/jcp.24.9.798.
Twelve out of 14 strains of Pseudomonas pseudomallei were inhibited in vitro by a combination of trimethoprim 1 mug per ml and sulphamethoxazole 20 mug per ml or by lower concentrations. Of the remaining strains, one was marginally more resistant and one was distinctly so. In tests utilizing two of the sensitive strains, inhibitory concentrations of the individual drugs exerted a bactericidal effect when combined.
14株类鼻疽假单胞菌中有12株在体外被每毫升含1微克甲氧苄啶和20微克磺胺甲恶唑的合剂所抑制,或被更低的浓度所抑制。其余菌株中,一株耐药性略强,一株则明显更强。在使用两株敏感菌株进行的试验中,单独药物的抑菌浓度联合使用时产生了杀菌作用。