[接触油漆和清漆有机溶剂工人的细胞化学和免疫学检查。I.β-葡萄糖醛酸酶和N-乙酰-β-氨基葡萄糖苷酶的活性。淋巴细胞中的糖原含量]

[Cytochemical and immunological examinations of workers exposed to the effects of organic solvents of paints and varnishes. I. Activity of beta-glucuronidase and N-acetyl-beta-glucosaminidase. Glycogen content in lymphocytes].

作者信息

Moszczyński P, Starek A, Lew-Władyka Z

出版信息

Med Pr. 1979;30(5):345-52.

Abstract

In workers, aged 26--55, occupationally exposed for 80--118 months to organic solvents of paints and varnishes containing benzene, toluene and xylene, beta-glucuronidase (GR) and N-acetyl-beta-glucosaminidase (GZ activities were determined and glycogen content in peripheral blood lymphocytes was evaluated. In addition to lymphocytopenia, the number of lymphocytes with cytoplasmic localization of GR and GZ and a decrease in glycogen content in those cells were found. The authors suppose these changes are due to toxic effects of aromatic hydrocarbons, present in organic solvents of paints and varnishes, upon lymphocytes.

摘要

在年龄为26 - 55岁、职业性接触含苯、甲苯和二甲苯的油漆及清漆有机溶剂达80 - 118个月的工人中，测定了β - 葡萄糖醛酸酶（GR）和N - 乙酰 - β - 氨基葡萄糖苷酶（GZ）的活性，并评估了外周血淋巴细胞中的糖原含量。除淋巴细胞减少外，还发现GR和GZ呈胞质定位的淋巴细胞数量以及这些细胞中的糖原含量减少。作者推测这些变化是由于油漆和清漆有机溶剂中存在的芳烃对淋巴细胞的毒性作用所致。

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