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接触苯及其同系物工人淋巴细胞中的N-乙酰-β-D-氨基葡萄糖苷酶

N-acetyl-beta-D-glucosaminidase in lymphocytes of workers exposed to benzene and its homologues.

作者信息

Moszczyński P, Lisiewicz J

出版信息

J Hyg Epidemiol Microbiol Immunol. 1984;28(1):11-6.

PMID:6715872
Abstract

In 108 workers having occupational contact with benzene and its homologues by 1 to 122 months, the activity of N-acetyl-beta-D-glucosaminidase (NAG) within the peripheral blood lymphocytes was estimated by means of cytochemical method. The benzene, the toluene and the xylene concentration at work stands was equal to 0-370, 0-580 and 0-560 mg/cu . m, respectively. In 41 workers having the service time equal to 55-122 months the NAG deficiency within the lymphocyte lysosomes was stated. Above phenomenon is probably due to disintegration of lysosomes caused by lipophilic properties of benzene.

摘要

对108名接触苯及其同系物1至122个月的工人，采用细胞化学方法测定其外周血淋巴细胞内N - 乙酰 - β - D - 氨基葡萄糖苷酶（NAG）的活性。工作场所苯、甲苯和二甲苯的浓度分别为0 - 370、0 - 580和0 - 560毫克/立方米。在41名工龄为55 - 122个月的工人中，发现淋巴细胞溶酶体内存在NAG缺乏现象。上述现象可能是由于苯的亲脂性导致溶酶体解体所致。

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