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[抗纤溶、预防水肿及降压药物在预防颅内动脉瘤再出血中的有效性]

[Effectiveness of antifibrinolytic, edema-preventing and hypotensive agents in the prevention of recurrent bleeding from intracranial aneurysms].

作者信息

Bromowicz J, Bryniarska D, Koniar-Danilewicz H, Danilewicz B

出版信息

Neurol Neurochir Pol. 1979 Nov-Dec;13(6):647-51.

PMID:514441
Abstract

On the basis of a material of 561 patients with ruptured intracranial aneurysms treated at the Department of Neurosurgery, Institute of Neurology, Medical Academy in Cracow in the years 1971 to 1977 the authors discuss the effectiveness of conservative treatment for prevention of recurrent bleeding from these aneurysms. The whole group of 561 patients were divied into two subgroups: 361 patients (group A) receiving standard antifibrilytic treatment, drugs preventing oedema formation and reducing the arterial blood pressure, and 254 patients (group B) who were not given antifibrinolytic agents and the other pharmacological agents were given to them only sporadivally. Recurrent bleeding developed in 8.86% of cases of group A and 11.02% in group B. The difference was not significant.

摘要

基于1971年至1977年期间在克拉科夫医学院神经病学研究所神经外科接受治疗的561例颅内动脉瘤破裂患者的资料,作者讨论了保守治疗预防这些动脉瘤再出血的有效性。561例患者被分为两个亚组:361例患者(A组)接受标准抗纤溶治疗、预防水肿形成和降低动脉血压的药物,254例患者(B组)未给予抗纤溶药物,其他药物仅偶尔给予。A组8.86%的病例发生再出血,B组为11.02%。差异无统计学意义。

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