el-Labban N, Lucas R B, Kramer I R
Br J Cancer. 1971 Sep;25(3):411-6. doi: 10.1038/bjc.1971.52.
In biopsies from the oral mucosa of 235 cases in which the diagnosis was lichen planus, keratosis or leukoplakia, mitotic values were calculated for the stratum basale (M.V. basal) and the stratum spinosum (M.V. spinous). The mean M.V. basal was significantly different from the mean M.V. spinous in the keratosis and leukoplakia groups, but not in the lichen planus group. Within the keratosis and leukoplakia groups, M.V. basal and M.V. spinous were significantly correlated. When each of the mean M.V.s was compared with the M.V.s for the other diagnostic groups, various significant differences were found. The M.V.s were examined in relation to the type of keratinization, the presence of acanthosis or atrophy, and the patient's age, but the M.V.s were not significantly related to these features.
在235例诊断为扁平苔藓、角化病或白斑的口腔黏膜活检病例中,计算了基底细胞层(M.V. 基底)和棘细胞层(M.V. 棘状)的有丝分裂值。在角化病和白斑组中,平均M.V. 基底与平均M.V. 棘状有显著差异,但在扁平苔藓组中无显著差异。在角化病和白斑组内,M.V. 基底和M.V. 棘状显著相关。当将每个平均M.V. 与其他诊断组的M.V. 进行比较时,发现了各种显著差异。研究了M.V. 与角化类型、棘皮症或萎缩的存在以及患者年龄的关系,但M.V. 与这些特征无显著相关性。