Keszler A, Cabrini R L
J Oral Pathol. 1983 Oct;12(5):330-5. doi: 10.1111/j.1600-0714.1983.tb00344.x.
Leukoplakia, lichen planus and carcinoma in situ of human oral mucosa were analysed histometrically by light microscopy. Leukoplakia lesions showed a greater total nuclear density than lichen planus lesions. They had a similar basal nuclear density to carcinomas in situ. The total and basal nuclear areas were notably greater in carcinomas in situ, indicating the presence of larger nuclei in comparison to those of other lesions. We believe it to be possible to make a differential diagnosis based on numerical variables.
通过光学显微镜对人类口腔黏膜的白斑、扁平苔藓和原位癌进行了组织计量学分析。白斑病变的总核密度高于扁平苔藓病变。它们的基底核密度与原位癌相似。原位癌的总核面积和基底核面积明显更大，表明与其他病变相比存在更大的细胞核。我们认为有可能基于数值变量进行鉴别诊断。
