普萘洛尔与急性间歇性卟啉症
Propranolol in acute intermittent porphyria.
作者信息
Menawat A S, Panwar R B, Kochar D K, Joshi C K
出版信息
Postgrad Med J. 1979 Sep;55(646):546-7. doi: 10.1136/pgmj.55.646.546.
Abstract
Twenty cases of acute intermittent porphyria were studied during the acute phase. Cardiovascular manifestations were noted in all the cases, with tachycardia in 20 and with hypertension in 17. Propranolol in doses ranging from 20--200 mg was given to all the cases and produced adequate control of tachycardia and hypertension. At follow-up, smaller doses of propranolol were found to maintain the pulse rate and BP within normal limits and also to prevent acute attacks.
摘要
在急性期对20例急性间歇性卟啉病患者进行了研究。所有病例均有心血管表现，20例有心动过速，17例有高血压。所有病例均给予剂量为20 - 200毫克的普萘洛尔，可有效控制心动过速和高血压。随访时发现，较小剂量的普萘洛尔可使脉搏率和血压维持在正常范围内，并预防急性发作。
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引用本文的文献
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Management of attacks of acute porphyria.急性卟啉病发作的管理。
Drugs. 1987 Nov;34(5):604-16. doi: 10.2165/00003495-198734050-00007.
本文引用的文献
1
The neuropathology of acute porphyria.急性卟啉病的神经病理学
J Pathol Bacteriol. 1956 Apr;71(2):495-509. doi: 10.1002/path.1700710222.
2
Acute intermittent porphyria: response of tachycardia and hypertension to propranolol.急性间歇性卟啉病：心动过速和高血压对普萘洛尔的反应
Br Med J. 1973 Aug 4;3(5874):257-60. doi: 10.1136/bmj.3.5874.257.
3
Letter: Hazard of propranolol in treatment of acute prophyria.信件：普萘洛尔治疗急性卟啉病的危害。
Br Med J. 1974 Oct 5;4(5935):47-8. doi: 10.1136/bmj.4.5935.47-c.
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