Kanarek R B, Collier G
Physiol Behav. 1979 Jul;23(1):141-5. doi: 10.1016/0031-9384(79)90134-3.
Rats were required to complete fixed ratio schedules (FR 20-FR 2560) of wheel turns to obtain access to food. By decreasing meal frequency and increasing meal size directly as functions of the fixed ratio requirement, animals controlled total daily food intake and body weight relatively constant until the highest ratio requirement was introduced. These functional changes in feeding patterns provide experimental support for theoretical models of optimal feeding strategies. At the highest ratio requirement, as animals lost weight, they increased running and therefore opportunities to feed, however, food intake continued to decrease with increasing exposure to this schedule. As rats on this schedule initiated feeding each time food became available, but did not eat large enough to this schedule. As rats on this schedule initiated feeding each time food became available, but did not eat large enough meals to maintain body weight, it is suggested that activity may interest with satiety mechanisms to produce termination of meals.
要求大鼠完成固定比率的轮转任务（FR 20 - FR 2560）以获取食物。通过直接根据固定比率要求降低进餐频率并增加进餐量，动物能够控制每日食物总摄入量和体重，使其相对保持恒定，直到引入最高比率要求。进食模式的这些功能性变化为最佳进食策略的理论模型提供了实验支持。在最高比率要求下，随着动物体重减轻，它们增加了跑动，从而增加了进食机会，然而，随着暴露于该任务的时间增加，食物摄入量继续减少。当处于该任务的大鼠每次食物可得时开始进食，但所吃食物量不足以维持体重，这表明活动可能与饱腹感机制相互作用导致进食终止。
