卟啉病与危及生命的危险药物。
Porphyria and the dangerous life-threatening drugs.
作者信息
Eales L
出版信息
S Afr Med J. 1979 Nov 24;56(22):914-7.
PMID:515871
Abstract
The dangerous life-threatening drugs have been identified in 153 acute attacks in 138 porphyric patients by establishing a consistent temporal relationship between the administration of a specific drug and the development of an acute attack. The drugs so identified have been supplemented by a number of others found to be porphyrogenic by testing with a recently devised rat model. Lists of the dangerous and the safe drugs have been compiled.
摘要
通过确定特定药物的使用与急性发作的发生之间一致的时间关系，在138名卟啉症患者的153次急性发作中识别出了危及生命的危险药物。通过使用最近设计的大鼠模型进行测试，发现了一些其他具有卟啉原性的药物，对这些已识别出的药物进行了补充。现已编制了危险药物和安全药物清单。
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