荚膜甲基球菌产生的蝶啶。新蝶呤2':3'-磷酸酯的分离与鉴定。
Pteridines produced by Methylococcus capsulatus. Isolation and identification of a neopterin 2':3'-phosphate.
作者信息
Urushibara T, Forrest H S, Hoare D S, Patel R N
出版信息
Biochem J. 1971 Nov;125(1):141-6. doi: 10.1042/bj1250141.
Abstract
Three pteridines have been isolated from the methane- or methanol-oxidizing bacterium Methylococcus capsulatus. Two of these are known compounds, 2-amino-6-carboxy-4-hydroxypteridine and 2-amino-4-hydroxy-6-methylpteridine. The third is shown by degradative and synthetic experiments to be l-threo-neopterin 2':3'-phosphate. Labelling experiments show that both the pteridine moiety and phosphate residue are derived from a single GTP molecule. The possible metabolic significance of these compounds in methanol oxidation is discussed.
摘要
从甲烷或甲醇氧化细菌荚膜甲基球菌中分离出了三种蝶啶。其中两种是已知化合物，即2-氨基-6-羧基-4-羟基蝶啶和2-氨基-4-羟基-6-甲基蝶啶。通过降解和合成实验表明，第三种是L-苏型新蝶呤2':3'-磷酸。标记实验表明，蝶啶部分和磷酸残基均来自单个GTP分子。讨论了这些化合物在甲醇氧化中可能的代谢意义。
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本文引用的文献
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Identification of a new phosphorylated pteridine from E. coli.从大肠杆菌中鉴定出一种新的磷酸化蝶啶。
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