Mirzoian P A, Promyslov M Sh
Ukr Biokhim Zh (1978). 1979 Sep-Oct;51(5):474-6.
It is shown that in the tissue of the human brain glial tumours the content of putrescine depends on the degree of the tumour malignization. In malignant gliomas (glioblastomas), as compared to the benign (astrocytomas), the content of putrescine is significantly higher. The content of spermidine in glial tumours of a malignancy different degree is twice as high as the level of this polyamine in the brain grey matter, and it is twice as low as in the white matter. The content of spermine in the brain glial tumours does not differ essentially from its level in the brain tissue.
结果表明，在人脑神经胶质瘤组织中，腐胺含量取决于肿瘤的恶性程度。与良性胶质瘤（星形细胞瘤）相比，恶性胶质瘤（胶质母细胞瘤）中的腐胺含量显著更高。不同恶性程度的神经胶质瘤中精胺的含量是脑灰质中该多胺水平的两倍，而比白质中的水平低一半。脑胶质瘤组织中精胺的含量与脑组织中的水平没有本质差异。
