Biochemical approaches to detection of viral related information in human acute leukemic cells.

Two biochemical markers that have been utilized for the detection of viral related information in human acute leukemic cells are: 1) The reverse transcriptase and 2) a high molecular weight RNA with viral related nucleotide sequences. This paper summarizes evidence that shows that the reverse transcriptase isolated from human acute leukemic cells is biochemically related to the reverse transcriptase from RNA tumor viruses.