Zippin C, Petrakis N L
West J Med. 1979 May;130(5):411-13.
In a study of 45 pairs of sisters-each pair including one sister with cancer of the breast and one without the disease-differences in marital and reproductive histories were observed. These differences included less frequent marriage, later marriage, fewer children, and a longer delay between date of marriage and the first pregnancy in the sisters with the disease. These findings appear to confirm presently known reproductive risk factors for cancer of the breast, but they also raise the possibility that unknown behavioral factors influencing the endocrine system may be delaying marriage and pregnancy.
在一项针对45对姐妹的研究中——每对姐妹中，一位患有乳腺癌，另一位未患此病——研究人员观察到了她们在婚姻和生育史方面的差异。这些差异包括结婚频率较低、结婚较晚、子女较少，以及患病姐妹在结婚日期与首次怀孕之间的间隔时间较长。这些发现似乎证实了目前已知的乳腺癌生殖风险因素，但它们也提出了一种可能性，即影响内分泌系统的未知行为因素可能正在推迟结婚和怀孕。
