Bartel H
Z Mikrosk Anat Forsch. 1979;93(3):537-44.
The study was intended to research the changes in the fine structure of thymus in old mice. The research were made in 3 strains of mice (Swiss, Porton and C 57 BL). In the stroma of the senile thymus takes place--full disappearance of mesenchymal reticular cells, as well as the considerable reduction of thymocytes, which were digested by macrophages. In the involuted thymus a large number of plasma cells and lymphoblasts were present. The author suggest the hypothesis that involution has an immunologic character.
该研究旨在探究老年小鼠胸腺精细结构的变化。研究针对3种品系的小鼠（瑞士小鼠、波顿小鼠和C 57 BL小鼠）展开。在老年胸腺的基质中发生了——间充质网状细胞完全消失，以及胸腺细胞显著减少，这些胸腺细胞被巨噬细胞消化。在退化的胸腺中存在大量浆细胞和淋巴母细胞。作者提出了退化具有免疫特性的假说。
