Bogdanovich N K
Zh Nevropatol Psikhiatr Im S S Korsakova. 1979;79(11):1487-91.
The hypothalamohypophyseal neurosecretory system (HHNS) was examined in the deceased from myocardial infarctions and chronic cardiac insufficiency. All 80 cases of infarctions showed in increased functional activity of the HHNS, irrespective of the time from the beginning of the disease. If the infarction was complicated by decompensation, the HHNS was characterized by hypervasopressure accompanied by occurrence of small vacuolized cells in the supraoptical nuclei with a low secretion content and high activity of biosynthetical enzymes, and a drop of secretion in the neurohypophysis. In chronic cardiac insufficiency (50 cases) there were 2 variants of changes in the HHNS, which correlated with the level of sympathetic nervous system activity (which was vitally determined from the diurnal catecholamine excretion). With high sympathetic activity, the changes in the HHNS were identical to those in myocardial infarctions, complicated by decompensation. The low activity was associated with HHNS depletion, which correlated with patients' nonsusceptibility to pathogenetic therapy.
对死于心肌梗死和慢性心功能不全的患者的下丘脑 - 垂体神经分泌系统（HHNS）进行了检查。所有80例梗死患者均显示HHNS功能活动增强，与疾病开始后的时间无关。如果梗死并发失代偿，HHNS的特征是血管压力过高，视上核出现小的空泡化细胞，分泌含量低且生物合成酶活性高，神经垂体分泌减少。在慢性心功能不全（50例）中，HHNS有两种变化类型，这与交感神经系统活动水平相关（从昼夜儿茶酚胺排泄量至关重要地确定）。交感神经活动高时，HHNS的变化与并发失代偿的心肌梗死相同。低活动与HHNS耗竭有关，这与患者对病因治疗的不敏感性相关。
