Bogdanovich N K
Arkh Patol. 1977;39(8):29-36.
The hypothalamo-hypophyseal neurosecretory system (HHNS) was studied in patients dying at various intervals after the onset of the first clinical manifestations of myocardial infarction. All the 75 cases were divided into two groups depending on the presence or absence of decompensation with disorders of the water-salt metabolism. Despite the duration and pattern of its course, myocardial infarction was shown to be always accompanied by a high activity of the HHNS and adrenal cortex, although different variants of its intensity could be distinguished by the studies of the secretory cycle in neurosecretory nuclei. When infarction was complicated by cardiac decompensation, there developed the state of hypervasopressinism constantly accompanied by hyperthrophy of the glomerular zone of the adrenal cortex producing aldosteron and by an increased concentration of intracellular sodium.
对在心肌梗死首次临床表现出现后不同时间间隔死亡的患者的下丘脑 - 垂体神经分泌系统（HHNS）进行了研究。根据是否存在伴有水盐代谢紊乱的失代偿情况，将所有75例患者分为两组。尽管心肌梗死病程的持续时间和模式不同，但研究表明，其始终伴有HHNS和肾上腺皮质的高活性，不过通过对神经分泌核分泌周期的研究可区分其强度的不同变体。当梗死并发心脏失代偿时，会出现高血管升压素状态，同时肾上腺皮质球状带持续增生，产生醛固酮，细胞内钠浓度升高。
