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[肝脏局灶性结节性增生]

[Focal nodular hyperplasia of the liver].

作者信息

Oprić M, Jovanović D M, Radojković P

出版信息

Acta Chir Iugosl. 1979;26(2):97-101.

PMID:517031
Abstract

Two cases of focal nodular hyperplasia of the liver were presented. The first case involved a 9 year old girl in whom palpable findings were made in the left lobe of the liver. The second case was incidentally discovered during a cholecystectomy. In both cases the laboratory results were within normal limits. The changes were found in the left portion of the liver. They were well delineated from the surrounding parenchyme and appeared septated. Central fibrotic contraction was also noted. The hepatocytes showed no changes. The biliary network was proliferated and the fibrous septae were of various thicknesses being in some places invaded by inflammatory infiltrate and irregular stretching. These alterations must be differentiated from hepatic adenoma because of the latter's malignant potential. Focal nodular hyperplastic lesions of the liver on the other hand are benign. The postoperative laboratory findings were also within normal limits. A lobectomy was performed in the first case and a partial resection and tumerectomy was carried out in the second case.

摘要

本文报告了两例肝脏局灶性结节性增生病例。第一例为一名9岁女孩,肝脏左叶可触及肿块。第二例是在胆囊切除术中偶然发现的。两例患者的实验室检查结果均在正常范围内。病变位于肝脏左侧,与周围实质界限清晰,呈分隔状,还可见中央纤维性收缩。肝细胞无变化,胆管网络增生,纤维间隔厚度不一,部分区域有炎性浸润及不规则伸展。由于肝腺瘤有恶变潜能,这些改变必须与肝腺瘤相鉴别。另一方面,肝脏局灶性结节性增生病变是良性的。两例患者术后实验室检查结果也均在正常范围内。第一例患者行肝叶切除术,第二例患者行部分切除术及肿瘤切除术。

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