Rust J
Electroencephalogr Clin Neurophysiol. 1975 Oct;39(4):321-7. doi: 10.1016/0013-4694(75)90095-4.
An experiment was carried out on 40 pairs of adult male twins to investigate the extent of genetical determination in the cortical auditory evoked potential. Tonal stimuli of 1 sec duration, at an intensity of 95 dB and a frequency of 100 c/sec, were used. The inter-stimulus interval was 33 sec and the bipolar evoked potential was measured between the CZ and T3 scalp positions. The reliability of the seven latency and amplitude measures was also calculated and this was taken into account in the subsequent genetic analysis. The biometrical gentical approach, which gives maximal information particularly on small samples, was used to analyse the data. A strong genetic influence was found on all the amplitude scores. The environment made no significant contribution to these. For the latencies there was some evidence for a genetic effect; however, this was not very strong and can well be interpreted as being due to between family environmental effects.
对40对成年男性双胞胎进行了一项实验,以研究皮质听觉诱发电位中基因决定的程度。使用了持续时间为1秒、强度为95分贝、频率为100赫兹的音调刺激。刺激间隔为33秒,并在头皮CZ和T3位置之间测量双极诱发电位。还计算了七个潜伏期和振幅测量值的可靠性,并在随后的基因分析中予以考虑。采用生物统计学基因方法分析数据,该方法尤其能从小样本中获取最大信息。结果发现,所有振幅分数都受到强烈的基因影响。环境对这些分数没有显著贡献。对于潜伏期,有一些证据表明存在基因效应;然而,这种效应不是很强,可以很好地解释为是由于家庭间环境效应所致。