通过血清酶和同工酶测定来检测酒精性心肌病。
Detection of alcoholic cardiomyopathy by serum enzyme and isoenzyme determination.
作者信息
Fink R, Marjot D H, Rosalki S B
出版信息
Ann Clin Biochem. 1979 May;16(3):165-6. doi: 10.1177/000456327901600135.
PMID:517982
Abstract
Serum creatine kinase and lactate dehydrogenase isoenzymes were studied in 73 patients with alcoholism, including two patients with clinical alcoholic cardiomyopathy and 28 patients with haemodynamic evidence (systolic time interval abnormality) of disordered myocardial function. No isoenzyme abnormalities suggestive of myocardial injury were observed. We conclude that isoenzyme examination is unsuitable for the early detection of myocardial damage from alcohol.
摘要
对73例酒精中毒患者进行了血清肌酸激酶和乳酸脱氢酶同工酶研究，其中包括2例临床诊断为酒精性心肌病的患者以及28例有心肌功能紊乱血流动力学证据（收缩期时间间期异常）的患者。未观察到提示心肌损伤的同工酶异常情况。我们得出结论，同工酶检查不适用于早期检测酒精所致的心肌损伤。
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