Lefebvre J, Dewailly D, Racadot A, Fossati P, Linquette M
Ann Endocrinol (Paris). 1979 Jul-Aug;40(4):433-4.
Plasma renin activity (P.R.A.) and plasma aldosterone were measured in twelve patients having hypopituitarism. Both mean values of this group were significantly lower than in normal subjects (P.R.A. recumbent: p less than 0.001, upright: p less than 0.001, plasma aldosterone: recumbent: p less than 0.02, upright: p less than 0.005). Hyporeninism is a controversed feature in hypopituitarism. Our preliminary data suggest that it is not directly correlated to ACTH or cortisol deficiency. Nevertheless it may explain the hypoaldosteronism prior reported in such patients.
对12例垂体功能减退患者测定了血浆肾素活性（P.R.A.）和血浆醛固酮。该组的两个平均值均显著低于正常受试者（P.R.A. 卧位：p<0.001，立位：p<0.001，血浆醛固酮：卧位：p<0.02，立位：p<0.005）。低肾素血症是垂体功能减退中一个有争议的特征。我们的初步数据表明，它与促肾上腺皮质激素（ACTH）或皮质醇缺乏无直接关联。然而，它可能解释此前报道的此类患者的醛固酮减少症。
