Pentz R, Brunn J
Arch Toxicol. 1979 Sep;42(4):311-5. doi: 10.1007/BF00334846.
After ingestion of 200-300 ml E 605-forte (i.e., 100-150 g parathion) a maximal concentration of 10.2 mg/l could be measured in the plasma of a male patient. An extracorporeal hemoperfusion was carried out using XAD-4 resin. The clearance valued 83 ml/min at a blood flow of 100 ml/min, which is about 40% higher compared to perfusion on activated charcoal. The described method is possibly an improved technique which could raise the rate of survival following parathion intoxication. In our study, however, the fatal end could not be prevented due to the intake of a very high dose of the poison.
摄入200 - 300毫升E 605 - forte(即100 - 150克对硫磷)后,一名男性患者血浆中可测得的最大浓度为10.2毫克/升。使用XAD - 4树脂进行了体外血液灌流。在血流量为100毫升/分钟时,清除率为83毫升/分钟,这比用活性炭进行灌流时高出约40%。所描述的方法可能是一种改进技术,可提高对硫磷中毒后的生存率。然而,在我们的研究中,由于摄入了非常高剂量的毒物,未能防止致命结局。