James P J, Warren G H
Aust Vet J. 1979 Jul;55(7):335-8. doi: 10.1111/j.1751-0813.1979.tb00420.x.
It was postulated that integrity of the sebaceous layer on the skin is important in maintaining resistance to fleece-rot. This hypothesis was tested in an experimenta of a 2 x 2 factorial design in which sebaceous layer disruption and wetting were the 2 treatments. The sebaceous layer was disrupted by applying a light petroleum solvent to the skin of the sheep. Fleece-rot occurred in all sheep (20) that were both wetted and had the sebaceous layer disrupted while 9/19 of those wetted but without the sebaceous layer disrupted developed fleece-rot. The fleece-rot lesions observed were more severe in sheep in the disrupted wetted treatments than in the intact wetted treatment. Interpretation of these differences was complicated by a possible reaction of the skin to the solvent used. The differences were not due to an effect of treatment on fleece wettability. No fleece-rot developed in the sheep not wetted and application of the solvent alone did not induce fleece-rot.
据推测，皮肤皮脂层的完整性对于维持抗羊毛腐烂能力很重要。这一假设在一项2×2析因设计实验中得到验证，其中皮脂层破坏和湿润是两种处理方式。通过向绵羊皮肤涂抹轻质石油溶剂来破坏皮脂层。在所有既被弄湿且皮脂层又被破坏的绵羊（20只）中都发生了羊毛腐烂，而在那些被弄湿但皮脂层未被破坏的绵羊中，19只里有9只发生了羊毛腐烂。在皮脂层被破坏且被弄湿的处理组中观察到的羊毛腐烂损伤比在皮脂层完整且被弄湿的处理组中更严重。由于皮肤可能对所用溶剂产生反应，这些差异的解读变得复杂。这些差异并非由于处理对羊毛湿润性的影响。未被弄湿的绵羊未发生羊毛腐烂，仅涂抹溶剂也未诱发羊毛腐烂。
