大鼠肝脏粗面内质网重质和轻质部分细胞色素P450的生物合成 - Suppr | 超能文献

The biosynthesis of cytochrome P450 by heavy and light rough endoplasmic reticulum of rat liver.

作者信息

Cooper M B, Craft J A, Estall M R, Rabin B R

出版信息

Biochem Biophys Res Commun. 1979 Nov 14;91(1):95-101. doi: 10.1016/0006-291x(79)90587-4.

DOI:10.1016/0006-291x(79)90587-4

Abstract

摘要

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The biosynthesis of cytochrome P450 by heavy and light rough endoplasmic reticulum of rat liver.大鼠肝脏粗面内质网重质和轻质部分细胞色素P450的生物合成

Biochem Biophys Res Commun. 1979 Nov 14;91(1):95-101. doi: 10.1016/0006-291x(79)90587-4.

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The role of components of the endoplasmic reticulum in the biosynthesis of cytochrome P-450.内质网成分在细胞色素P-450生物合成中的作用。

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The biosynthesis of cytochrome P450 by rough endoplasmic reticulum in vitro. A significant proportion of newly-biosynthesised cytochrome P450 is resistant to proteolytic digestion in intact vesicles.体外糙面内质网对细胞色素P450的生物合成。相当一部分新生物合成的细胞色素P450在完整囊泡中对蛋白水解消化具有抗性。

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Biosynthesis of rat liver cytochrome P-450 in mitochondria-associated rough endoplasmic reticulum and in rough microsomes in vivo.大鼠肝脏细胞色素P-450在线粒体相关粗面内质网及体内粗面微粒体中的生物合成。

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[The effect of dipin on inductive synthesis of cytochrome P450 in the endoplasmic reticulum of rat liver cells].[双嘧达莫对大鼠肝细胞内质网中细胞色素P450诱导合成的影响]

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Differential time-course of induction of rat liver gamma-glutamyltransferase and drug-metabolizing enzymes in the endoplasmic reticulum, Golgi and plasma membranes after a single phenobarbital injection. Evaluation of protein variations by two-dimensional electrophoresis.单次注射苯巴比妥后，大鼠肝脏内质网、高尔基体和质膜中γ-谷氨酰转移酶及药物代谢酶诱导的差异时程。通过二维电泳评估蛋白质变化。

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The physical association between rat liver mitochondria and rough endoplasmic reticulum. II. Possible role RER-MT complexes play in the biosynthesis of cytochrome P-450.大鼠肝脏线粒体与粗面内质网之间的物理联系。II. 粗面内质网-线粒体复合物在细胞色素P-450生物合成中可能发挥的作用。

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Binding of polysomes in vitro with endoplasmic membrane prepared from rat liver. II. Possible involvement of cytochrome P-450 in the binding.体外多核糖体与大鼠肝脏内质膜的结合。II. 细胞色素P-450可能参与结合过程。

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D-galactosamine hepatotoxicity. 3. Normoactive smooth endoplasmic reticulum and modification by phenobarbital.D-半乳糖胺肝毒性。3. 正常活性的滑面内质网及苯巴比妥的修饰作用。

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Effect of cyclic AMP on the phenobarbital induced increase in cytochrome P-450 and hypertrophy of the endoplasmic reticulum of the rat liver.环磷酸腺苷对苯巴比妥诱导的大鼠肝脏细胞色素P - 450增加及内质网肥大的影响。

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Newly biosynthesized cytochrome P-450 associated with the golgi apparatus from livers of rats induced with phenobarbital.新生物合成的细胞色素P-450与用苯巴比妥诱导的大鼠肝脏的高尔基体相关。

Biochem J. 1981 Mar 15;194(3):691-7. doi: 10.1042/bj1940691.