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[乙型肝炎表面抗原在膀胱血吸虫病患者中的扩散]

[Diffusion of hepatitis B surface antigens in subjects with bladder schistosomiasis].

作者信息

Nuti M, Abdullahi Elmi S, Alario C

出版信息

Boll Ist Sieroter Milan. 1979 Jul 31;58(3):220-3.

PMID:518754
Abstract

The problem of the relationship between the surface B antigen and the parasitosis characterized by active penetration of the larvae through the skin has not yet been resolved. Conflicting results have been reported lately on this problem even though it is currently believed that HBsAg is found more often among patients infected by parasites than among healthy subjects. Serum samples from 67 Somalian patients infected by S. haematobium were tested for the presence of the surface B antigen by ELISA method. The HBsAg was found in 19.4 per cent of these patients, while among controls (90 cases) the frequency of HBsAg was of 10 per cent. A comparative analysis of the results obtained with various methods in Somalia shows that the frequency of HBsAg among subjects with urinary schistosomiasis is of 25.9 per cent with indirect haemoagglutination (IHA), of 19.4 per cent with ELISA method and of 14.8 per cent with radioimmunoassay (RIA). These observations seem to indicate that the problem of an increased frequency of HBsAg among patients with urinary schistosomiasis needs further investigation.

摘要

关于体表B抗原与以幼虫经皮肤主动侵入为特征的寄生虫病之间的关系问题尚未得到解决。尽管目前认为在寄生虫感染者中发现乙肝表面抗原(HBsAg)的频率高于健康受试者,但最近关于这个问题的报道结果相互矛盾。采用酶联免疫吸附测定(ELISA)法对67例感染埃及血吸虫的索马里患者的血清样本进行了表面B抗原检测。在这些患者中,19.4%检测出HBsAg,而在对照组(90例)中,HBsAg的检出频率为10%。索马里采用各种方法所获结果的对比分析表明,在尿路血吸虫病患者中,间接血凝试验(IHA)检测HBsAg的频率为25.9%,ELISA法为19.4%,放射免疫测定(RIA)法为14.8%。这些观察结果似乎表明,尿路血吸虫病患者中HBsAg频率增加的问题需要进一步研究。

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