[Cellular ultrastructure of the hepatic sinusoid in partially hepatectomized rats].

In male Wistar rats weighing 160-200 g 2/3 of the liver tissue was removed. As a result the phase modifications of lysosome structures in Kupffer's cells have been observed. 2.5 hours after operation the number of primary lysosomal granules increased, 9 hours later an augmentation in size and polymorphism of lysosomes was revealed. At the moment of hepatocyte mitotic peak, i. e. 30 hours after partial liver removal mainly secondary lysosomes were detected in Kupffer's cells. On the contrary, 48 hours following operation the number of new wave of accumulation of primary lysosomal granules was seen. In endothelial cells the lipid infiltration was prevalent especially at the hepatocyte mitotic peak period. The data obtained indicate specific relationship of ultrastructural modifications in sinusoidal cells and phases of the liver reparative regeneration.