Panin L E, Poliakov L M
Biull Eksp Biol Med. 1979 Sep;88(9):267-9.
It has been shown that high density lipoproteins obtained by ultracentrifugation and loaded with cholesterol and pregnenolone exert a stimulant effect on in vitro production of glucocorticoids by rat adrenals. Low density native lipoproteins possess an inhibitory effect connected with the protein component. The action of various blood serum lipoproteins on steroidogenesis in rat adrenals has significantly different mechanisms.
已经表明，通过超速离心获得并负载胆固醇和孕烯醇酮的高密度脂蛋白对大鼠肾上腺体外产生糖皮质激素具有刺激作用。低密度天然脂蛋白具有与蛋白质成分相关的抑制作用。各种血清脂蛋白对大鼠肾上腺类固醇生成的作用具有明显不同的机制。
