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[某些保存液灌注期间小肠组织血液屏障的通透性]

[Permeability of histohematic barriers of the small intestine during perfusion with some preserving solutions].

作者信息

Kulik B P, Genyk S N, Krysa V M, Goncharenko R V, Kostiuk V M

出版信息

Biull Eksp Biol Med. 1979 Sep;88(9):286-8.

PMID:519019
Abstract

The permeability changes in histohematic barriers of the isolated small intestine loops of laboratory white rats whose vessels were perfused with 0.85% sodium chloride, Ringer-Lock, Hanks and Collins-2 solutions as well as with hemodez and aminopeptide were studied. The amount of the fluid flowing off the vessels, perfusate penetration into the intestinal lumen and its transudation through the serous membrane were determined. It was concluded that the slightest disturbance in the small intestine histohematic barrier was observed during perfusion of the vessels with Collins-2 solution. The above method is recommended for testing the comparative characteristics of the preserving solution.

摘要

研究了用0.85%氯化钠、林格-洛克液、汉克斯液和柯林斯-2液以及血代和氨肽灌注血管的实验白鼠离体小肠袢组织血液屏障的通透性变化。测定了从血管流出的液体量、灌注液渗入肠腔的情况及其通过浆膜的渗出情况。得出结论,在用柯林斯-2液灌注血管时,观察到小肠组织血液屏障受到的干扰最小。推荐上述方法用于测试保存液的比较特性。

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