Burge P S, Prankerd T A, Richards J D, Sare M, Thompson D S, Wright P
Lancet. 1975 Oct 4;2(7936):621-4. doi: 10.1016/s0140-6736(75)90111-7.
The quality of life in leukaemia is as important as its quantity. In fifty-one patients the quality and quantity of life were improved by less aggressive treatment than is usual. By not trying to induce complete remission at all costs, the mobidity and early mortality were reduced and at least an equivalence in survival was obtained.