Benfer J, Struck H
Chirurg. 1979 Aug;50(8):508-13.
In an animal experiment study the effect of collagen sponge treatment on skin wounds was examined. In a test for defense mechanism, the bandage material was accepted without any disturbance of the surrounding tissue. It could also be removed without any damage to the wound area while renewing the covering bandage. In contrast to the controls, there was a statistically significant difference in the decreasing wound area. No tract formation of the wound edges was observed in the experimental group, and histologically the wounds showed an earlier fiber formation with functional orientation toward the wound surface. The advantages of treatment using collagen instead of inert material include better compatibility, a positive cosmetic effect, and a stimulation of wound healing without the necessity of a two-stage transplantation.
在一项动物实验研究中，检测了胶原蛋白海绵治疗对皮肤伤口的效果。在防御机制测试中，绷带材料被接受，周围组织未受到任何干扰。在更换覆盖绷带时，它也可以被移除而不会对伤口区域造成任何损伤。与对照组相比，伤口面积减小存在统计学显著差异。实验组未观察到伤口边缘形成条索，组织学上伤口显示出更早的纤维形成，且纤维功能上朝向伤口表面。使用胶原蛋白而非惰性材料进行治疗的优点包括更好的相容性、积极的美容效果以及无需两阶段移植即可促进伤口愈合。
