色甘酸钠对大鼠皮肤伤口愈合及伤口中胶原蛋白含量的影响。
The effect of disodium cromoglycate on the skin wound healing and collagen content in the wounds of rats.
作者信息
Dabrowski R, Drobnik J
机构信息
Department of Pathophysiology, School of Medicine, Lódź, Poland.
出版信息
Acta Physiol Pol. 1990;41(4-6):195-8.
The effect of disodium cromoglycate on skin wound healing and collagen formation in the wounds was studied. Disodium cromoglycate (a mast cell stabilizer) administered to the rats in a dose of 2 mg/animal was found to retard wound healing and markedly increased wound surface in all examined days (3rd, 5th, 7th, 10th, 14th day of healing). The mast cell stabilizer injected directly into wounds decreased collagen content, especially on 10th and 14th day of the healing process.
研究了色甘酸钠对皮肤伤口愈合及伤口中胶原蛋白形成的影响。给大鼠按2毫克/只的剂量注射色甘酸钠（一种肥大细胞稳定剂），发现在所有检查日（愈合的第3、5、7、10、14天）均会延缓伤口愈合，并显著增大伤口面积。直接注射到伤口中的肥大细胞稳定剂会降低胶原蛋白含量，尤其是在愈合过程的第10天和第14天。
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