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Acquired and native resistance of Staphylococcus aureus to cephalexin and other beta-lactam antibiotics.

作者信息

Kayser F H, Benner E J, Hoeprich P D

出版信息

Appl Microbiol. 1970 Jul;20(1):1-5. doi: 10.1128/am.20.1.1-5.1970.

DOI:10.1128/am.20.1.1-5.1970
PMID:5201887
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC376855/
Abstract

Staphylococcus aureus cells that are initially susceptible to cephalexin can be induced to acquire intrinsic resistance to cephalexin in comparatively few steps. Concomitantly, resistance to cephalothin, oxacillin, and dicloxacillin increases. By population analysis, there is heteroresistance to cephalexin in some strains of S. aureus. Heterogeneity in colonial morphology on prolonged incubation in the presence of subinhibitory concentrations of cephalexin may constitute an expression of such heteroresistance.

摘要

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本文引用的文献

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Production of Staphylococcus Strains Resistant to Various Concentrations of Penicillin.对不同浓度青霉素具有抗性的葡萄球菌菌株的产生
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Cephalexin: a review of its antibacterial, pharmacological and therapeutic properties.头孢氨苄：对其抗菌、药理和治疗特性的综述。
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[On the oxacillin resistance of pathogenic Staphylococci. I. Nature of resistance against oxacillin in Staphylococcus pyogenes aureus].[关于致病性葡萄球菌对苯唑西林的耐药性。I. 金黄色酿脓葡萄球菌对苯唑西林的耐药性质]
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