Grigorova R, Petkova M, Ilieva T, Kemileva Z, Iordanov I
Eksp Med Morfol. 1979;18(4):220-3.
The authors examined arterial blood pressure and excretion of pregnanetriol and pregnanediol in urine of adult male rats of Westar strain under normal conditions and after thymectomy. There was an elevation of arterial blood pressure after 45th day of thymectomy. Excretion of pregnanediol was increased on the 30th day, but that of pregnanetriol on the 60th day after removal of the gland. The increased excretion of both progesterone metabolites was connected with increased renal function, which probably played pathogenic role in postthymectomized hypertensive reaction.
作者研究了正常条件下以及胸腺切除术后成年雄性韦斯塔大鼠的动脉血压、尿中孕三醇和孕二醇的排泄情况。胸腺切除术后第45天动脉血压升高。切除腺体后第30天孕二醇排泄增加，而孕三醇排泄在第60天增加。两种孕酮代谢产物排泄增加与肾功能增强有关，这可能在胸腺切除术后的高血压反应中起致病作用。
