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一些99mTc肝胆显像剂的吸收剂量估计

Absorbed dose estimation of some 99mTc-hepatobiliary agents.

作者信息

Koutoulidis C, Chiotellis E, Lymberis C

出版信息

Eur J Nucl Med. 1979 Dec;4(6):441-4. doi: 10.1007/BF00300842.

Abstract

The absorbed dose estimates of several organs after administration in humans of six new hepatobiliary agents (five 99mTc-Pyridoxal amino acid complexes and the 99mTc-HIDA) are presented in comparison with 131I-Rose-Bengal. The results indicated that the radiation doses absorbed by the total body and gonads as well as by the critical organ (upper part of the large intestine) are significantly lower than those of Rose Bengal. Therefore, the new 99mTc-agents can be safely applied to humans.

摘要

将六种新型肝胆显像剂(五种99mTc - 吡哆醛氨基酸络合物和99mTc - HIDA)施用于人体后,给出了几个器官的吸收剂量估计值,并与131I - 玫瑰红进行了比较。结果表明,全身、性腺以及关键器官(大肠上部)吸收的辐射剂量显著低于玫瑰红。因此,新型99mTc显像剂可安全应用于人体。

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