Spiess H, Mays C W
Eur J Pediatr. 1979;132(4):271-6. doi: 10.1007/BF00496850.
Exostoses are benign cartilaginous tumors of bone. They can occur naturally or be induced by radiation therapy during the time of skeletal growth. We have observed exostoses in 28 of 218 children given repeated injections of radioactive bone-seeking 224Ra. The younger the age at irradiation, the higher the incidence of exostoses. Boys are more susceptible than girls. To our knowledge, none of these radiation-induced exostoses have become malignant, although 36 of these children have developed bone sarcomas elsewhere in the skeleton.
外生骨疣是骨的良性软骨肿瘤。它们可自然发生，也可在骨骼生长期间由放射治疗诱发。我们在218名反复注射亲骨性放射性224镭的儿童中观察到28例有外生骨疣。照射时年龄越小，外生骨疣的发生率越高。男孩比女孩更易患病。据我们所知，这些辐射诱发的外生骨疣均未恶变，尽管其中36名儿童在骨骼其他部位发生了骨肉瘤。
