Wick R R, Gössner W
Health Phys. 1983;44 Suppl 1:187-95. doi: 10.1097/00004032-198306001-00015.
We are following 1531 patients treated with 224Ra from 14 hospitals in the F.R.G. and 267 control patients with ankylosing spondylitis not treated with any form of ionizing radiation. Since 1970 three cases of malignant tumour in the skeleton have been found among 224Ra-treated patients with skeletal doses below 90 rad compared with 0.4-0.6 expected. Two of these three cases were tumours of the bone marrow. An effect of 224Ra on the haematopoietic system cannot be excluded. Also, seven cases of cataract were found among 274 224Ra patients. The mean time since 224Ra treatment was 26 yr. The mean age at diagnosis was 66 yr. The cataract incidence was not unusual for people of this age.
我们正在跟踪德国14家医院中接受224镭治疗的1531名患者，以及267名未接受任何形式电离辐射治疗的强直性脊柱炎对照患者。自1970年以来，在骨骼剂量低于90拉德的接受224镭治疗的患者中，发现了3例骨骼恶性肿瘤，而预期为0.4 - 0.6例。这3例中的2例是骨髓肿瘤。不能排除224镭对造血系统的影响。此外，在274名接受224镭治疗的患者中发现了7例白内障。自接受224镭治疗后的平均时间为26年。诊断时的平均年龄为66岁。这个年龄段的人群白内障发病率并无异常。
