Sträuli P, Maignan M F
Experientia. 1979 Dec 15;35(12):1582-4. doi: 10.1007/BF01953206.
Normal rat lymphocytes and cells of 2 highly invasive tumors, the L5222 rat leukemia and the VW rabbit carcinoma, were inoculated in vitro on the mesothelial surface of the visceral wall of the rat embryo yolk sac. After 48 h, lymphocytes, without any damage being inflicted on the mesothelial cells, had penetrated deeply into the yolk sac wall, whereas both kinds of cancer cells had destroyed the mesothelial cells, but not advanced beyond the basal lamina.
将正常大鼠淋巴细胞以及两种具有高度侵袭性肿瘤的细胞，即L5222大鼠白血病细胞和VW兔癌细胞，在体外接种于大鼠胚胎卵黄囊脏壁的间皮表面。48小时后，淋巴细胞在未对间皮细胞造成任何损伤的情况下，已深深侵入卵黄囊壁，而两种癌细胞均破坏了间皮细胞，但未突破基底层。
