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2-巯基丙酰甘氨酸对辐射诱导的小鼠脾脏重量变化的影响

Modification of radiation-induced spleen weight changes in mice by 2-mercaptopropionylglycine.

作者信息

Saini M R, Devi P U

出版信息

Experientia. 1979 Dec 15;35(12):1628-9. doi: 10.1007/BF01953233.

DOI:10.1007/BF01953233
PMID:520478
Abstract

It was found that the MPG partially protects the spleen against weight loss due to radiation, and exaggerates the compensatory reaction in the tissue during recovery. It is also concluded that MPG protects the stem cells in the spleen, which helps to restore the peripheral blood by extramedullary erythropoiesis.

摘要

研究发现，MPG可部分保护脾脏免受辐射导致的体重减轻，并在恢复过程中加剧组织中的代偿反应。还得出结论，MPG可保护脾脏中的干细胞，这有助于通过髓外造血恢复外周血。

相似文献

1
Modification of radiation-induced spleen weight changes in mice by 2-mercaptopropionylglycine.2-巯基丙酰甘氨酸对辐射诱导的小鼠脾脏重量变化的影响
Experientia. 1979 Dec 15;35(12):1628-9. doi: 10.1007/BF01953233.
2
Radiation protection of pronormoblasts and normoblasts by 2-mercaptopropionylglycine (MPG).2-巯基丙酰甘氨酸（MPG）对早幼红细胞和正成红细胞的辐射防护作用
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Protection of mouse thymus against cobalt-60 radiation by 2-mercaptopropionylglycine (MPG).2-巯基丙酰甘氨酸（MPG）对小鼠胸腺的钴-60辐射防护作用。
J Radiat Res. 1977 Aug;18(3):211-24. doi: 10.1269/jrr.18.211.
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Weight changes in mice after intrauterine treatment with MPG (2-mercaptopropionylglycine) against I131 irradiation.用MPG（2-巯基丙酰甘氨酸）对小鼠进行宫内治疗以对抗I131辐射后的体重变化。
Experientia. 1981;37(8):898-9. doi: 10.1007/BF01985702.
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Protection from body weight loss by 2-mercaptopropionylglycine (MPG) in growing mice irradiated in utero with gamma radiation.2-巯基丙酰甘氨酸（MPG）对子宫内受γ射线照射的生长小鼠体重减轻的保护作用。
Experientia. 1982 Aug 15;38(8):962-3. doi: 10.1007/BF01953678.
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Radiation protection of bone marrow lymphocytes by 2-mercaptopropionylglycine (MPG).2-巯基丙酰甘氨酸（MPG）对骨髓淋巴细胞的辐射防护作用
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MPG (2 mercaptopropionylglycine) protection in thymus & spleen against 1500 R gamma radiation.2-巯基丙酰甘氨酸（MPG）对胸腺和脾脏的1500伦琴γ射线辐射的防护作用
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2-Mercaptopropionylglycine protection against growth-inhibiting effects in utero irradiated mice.2-巯基丙酰甘氨酸对子宫内受照射小鼠生长抑制作用的保护作用。
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Radiation protection of mouse liver by 2-mercaptopropionylglycine.2-巯基丙酰甘氨酸对小鼠肝脏的辐射防护作用
J Radiat Res. 1977 Aug;18(3):206-10. doi: 10.1269/jrr.18.206.

引用本文的文献

1
Weight changes in mice after intrauterine treatment with MPG (2-mercaptopropionylglycine) against I131 irradiation.用MPG（2-巯基丙酰甘氨酸）对小鼠进行宫内治疗以对抗I131辐射后的体重变化。
Experientia. 1981;37(8):898-9. doi: 10.1007/BF01985702.

本文引用的文献

1
Effects of X-ray on lymphoid and hemopoietic tissues of albino mice.X射线对白化小鼠淋巴组织和造血组织的影响。
Blood. 1948 Nov;3(11):1259-74.
2
Mechanism of protective action of glutathione against whole body irradiation.谷胱甘肽对全身照射的保护作用机制。
Proc Soc Exp Biol Med. 1951 Feb;76(2):396-8. doi: 10.3181/00379727-76-18502.
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QUANTITATION OF CELLULAR RESPONSES IN THE MOUSE SPLEEN AFTER IRRADIATION.
Ann N Y Acad Sci. 1964 Mar 31;114:557-70. doi: 10.1111/j.1749-6632.1964.tb53608.x.
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Effect of chemical protection and bone marrow treatment on radiation injury in mice.
Blood. 1958 Jul;13(7):665-76.
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Intestinal damage by radiation and its chemical modification.
Nature. 1957 Dec 7;180(4597):1278. doi: 10.1038/1801278a0.
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Radiation dose reduction by cysteine.半胱氨酸降低辐射剂量。
J Cell Comp Physiol. 1953 Dec;42(3):327-41. doi: 10.1002/jcp.1030420302.
7
Biphasic pattern of thymus regeneration after whole-body irradiation.全身照射后胸腺再生的双相模式。
J Exp Med. 1969 Mar 1;129(3):445-57. doi: 10.1084/jem.129.3.445.
8
Protection of mouse thymus against cobalt-60 radiation by 2-mercaptopropionylglycine (MPG).2-巯基丙酰甘氨酸（MPG）对小鼠胸腺的钴-60辐射防护作用。
J Radiat Res. 1977 Aug;18(3):211-24. doi: 10.1269/jrr.18.211.
9
Radiation protection of mouse liver by 2-mercaptopropionylglycine.2-巯基丙酰甘氨酸对小鼠肝脏的辐射防护作用
J Radiat Res. 1977 Aug;18(3):206-10. doi: 10.1269/jrr.18.206.
10
Radiation protection of bone marrow lymphocytes by 2-mercaptopropionylglycine (MPG).2-巯基丙酰甘氨酸（MPG）对骨髓淋巴细胞的辐射防护作用
Experientia. 1978 Dec 15;34(12):1627-8. doi: 10.1007/BF02034716.