组胺、5-羟色胺和缓激肽诱导大鼠滑膜血管通透性增强的时程及不应期
Time courses and refractoriness of enhanced vascular permeability induced by histamine, serotonin and bradykinin in synovialis of the rat.
作者信息
Bignold L P, Lykke A W
出版信息
Experientia. 1979 Dec 15;35(12):1645-7. doi: 10.1007/BF01953245.
PMID:520486
Abstract
Enhanced vascular permeability induced in synovialis of the rat by histamine and serotonin lasts 5-15 min and that induced by bradykinin less than 5 min. Synovialis of the rat becomes refractory to the permeability effects of repeated doses of each of these substances in the hour following initial application.
摘要
组胺和5-羟色胺诱导的大鼠滑膜血管通透性增强持续5-15分钟，而缓激肽诱导的则少于5分钟。在首次应用后的一小时内，大鼠滑膜对这些物质重复给药的通透性效应产生耐受。
Zotero 插件