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移植物抗宿主综合征幸存者中淋巴瘤发病率增加。

Increased incidence of lymphomas in survivors of the host-versus-graft syndrome.

作者信息

Cornelius E A

出版信息

Experientia. 1979 Dec 15;35(12):1672-3. doi: 10.1007/BF01953263.

Abstract

When (SB)F1 spleen cells were injected into perinatal parental B strain mice a lethal runting syndrome was induced. The survivors showed a significantly increased incidence of lymphomas in old age. The tumors occurred much later and less frequently than in the reverse reaction, B leads to (SB)F1 GVHD.

摘要

当将(SB)F1脾细胞注射到围产期的亲代B品系小鼠体内时,会诱发一种致死性发育迟缓综合征。幸存者在老年时淋巴瘤的发病率显著增加。这些肿瘤出现的时间比反向反应(B导致(SB)F1移植物抗宿主病)要晚得多,且频率更低。

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